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After restraint stress, mice with high and low immobility time have a different neurochemical and behavioral profile MV&Z
Reis-Silva, Thiago; Lima, Ana Paula; Moreira, Natalia; Calefi, Atilio; Sandini, Thaísa Meira; Florio, Jorge Camilo; Bernardi, Maria Martha.
High and low immobility on the tail suspension test is a common tool for assessing antidepressant drug effects. However, those parameters might be a natural phenotype present in the mice population and could be selected through behavior evaluation without an induced-drug behavior need. High immobility has been also related to depressed-like behavior, that in humans are characterized by wide range of symptoms, such as anhedonia, anxiety and tiredness. 
Tipo: Info:eu-repo/semantics/article Palavras-chave: Stress; Mice; Behavior; Animal.
Ano: 2016 URL: http://www.revistamvez-crmvsp.com.br/index.php/recmvz/article/view/31107
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Unpredictable stress in adolescnt mice: long-term effects on neurochemistry and on behavior MV&Z
Lima, Ana Paula; Reis-Silva, Thiago Marinho; Sandini, Thaísa Meira; Massoco, Cristina.
Adolescence is one of the most critical period of development and has a great importance to the health of an adult life. Stressors or traumatic events during this period are associated with changes in the development and plasticity of the neuroendocrine system predisposing the individual to psychiatric disorders as related to anxiety or depression. However stress in adolescence is a very discussed topic and there are few studies about the longterm effects of stress during this period. Therefore, this study aims to assess the impacts in adulthood of unpredictable stress during adolescence on behavioral tests
Tipo: Info:eu-repo/semantics/article
Ano: 2016 URL: http://www.revistamvez-crmvsp.com.br/index.php/recmvz/article/view/31115
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